Experience breathtaking scenery and cultural wonders on Mississippi river cruises. Explore iconic waterways, enjoy gourmet dining, and create unforgettable memories. Book with no additional fees and get the best cruise deals.

Book Mississippi river cruises online and save

Cruisebound

Viking River Cruises

21 Night Mississippi River Odyssey aboard the Viking Mississippi departing from New Orleans, Louisiana, on 2027-07-06, cruises to Baton Rouge, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, United States, Memphis, Tennessee, Memphis, Tennessee, Paducah, Kentucky, Cape Girardeau, Missouri, St. Louis, Missouri, St. Louis, Missouri, Alton, Illinois, Hannibal, Missouri, Burlington, Canada, Dubuque, Iowa, La Crosse, Wisconsin, Red Wing, Minnesota and Saint Paul, United States, starting at 15998.0 per person.

21 Night Mississippi River Odyssey

7 Night Heartland Of America aboard the Viking Mississippi departing from Saint Paul, United States, on 2028-09-05, cruises to Red Wing, Minnesota, La Crosse, Wisconsin, Dubuque, Iowa, Burlington, Canada and Hannibal, Missouri, starting at 6799.0 per person.

7 Night Heartland Of America

14 Night America's Great River aboard the Viking Mississippi departing from Saint Paul, United States, on 2028-08-01, cruises to Red Wing, Minnesota, La Crosse, Wisconsin, Dubuque, Iowa, Burlington, Canada, Hannibal, Missouri, St. Louis, Missouri, Memphis, Tennessee, Greenville, United States, Vicksburg, Mississippi, Natchez, Mississippi, Baton Rouge, Louisiana and New Orleans, Louisiana, starting at 12999.0 per person.

14 Night America's Great River

7 Night Mississippi & Ohio River Explorer aboard the Viking Mississippi departing from Louisville, Kentucky, on 2027-06-15, cruises to Owensboro, KY, Paducah, Kentucky, Memphis, Tennessee and Memphis, Tennessee, starting at 6299.0 per person.

7 Night Mississippi & Ohio River Explorer

14 Night Bayous,Blues & Bluegrass aboard the Viking Mississippi departing from Louisville, Kentucky, on 2027-11-09, cruises to Owensboro, KY, Paducah, Kentucky, Memphis, Tennessee, Memphis, Tennessee, Greenville, United States, Vicksburg, Mississippi, Natchez, Mississippi, Baton Rouge, Louisiana and New Orleans, Louisiana, starting at 10998.0 per person.

14 Night Bayous,Blues & Bluegrass

14 Night The Big Easy To The Gateway City aboard the Viking Mississippi departing from New Orleans, Louisiana, on 2027-07-06, cruises to Baton Rouge, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, United States, Memphis, Tennessee, Memphis, Tennessee, Paducah, Kentucky, Cape Girardeau, Missouri, St. Louis, Missouri and St. Louis, Missouri, starting at 9499.0 per person.

14 Night The Big Easy To The Gateway City

7 Night Heartland Of America aboard the Viking Mississippi departing from Saint Paul, United States, on 2027-08-31, cruises to Red Wing, Minnesota, La Crosse, Wisconsin, Dubuque, Iowa, Burlington, Canada and Hannibal, Missouri, starting at 6499.0 per person.

7 Night Mississippi & Ohio River Explorer aboard the Viking Mississippi departing from Louisville, Kentucky, on 2027-11-09, cruises to Owensboro, KY, Paducah, Kentucky, Memphis, Tennessee and Memphis, Tennessee, starting at 5999.0 per person.

7 Night Nashville,Memphis & The Cumberland aboard the Viking Mississippi departing from Nashville, Tennessee, on 2026-11-17, cruises to Clarksville, Tennessee, Paducah, Kentucky, Cape Girardeau, Missouri, Memphis, Tennessee and Memphis, Tennessee, starting at 4799.0 per person.

7 Night Nashville,Memphis & The Cumberland

7 Night Mississippi Delta Explorer aboard the Viking Mississippi departing from New Orleans, Louisiana, on 2027-01-26, cruises to Baton Rouge, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, United States and Memphis, Tennessee, starting at 3999.0 per person.

7 Night Mississippi Delta Explorer

Popular Sailings

Browse Cruise Lines

New Orleans, Louisiana

The birthplace of American jazz, New Orleans exudes a festive atmosphere along the balcony-lined Bourbon Street. Here, in the heart of the French Quarter, soulful rhythms lift the spirit, especially during the city’s Mardi Gras celebration. Founded by Fre

The Lower Mississippi region is dotted with historic mansions; Darrow is the gateway to these grand homes, meticulously kept to preserve the memory of early Southern American history. Here, imposing houses share the riverscape with moss-draped oak trees a

Boasting more than 140 buildings on the National Register of Historic Places, St. Francisville is set along one of the most historic bluffs of the Mississippi. The town is said to be “two miles long and two yards wide” because it was originally built on a

Baton Rouge paints a historic picture on the eastern bank of the Mississippi. Its early success was due to its flood-free location upon the first natural bluff north of The Delta. French explorer Pierre Le Moyne, Sieur d’Iberville, named the city after a 

Baton Rouge, Louisiana

Natchez has one of the highest concentrations of historic Southern estates in the country. More than 200 perfectly preserved homes line its avenues. It is the oldest city on the Mississippi, established in 1716 by French colonists and named for the Natche

Natchez, Mississippi

Located on a high bluff where the Yazoo River flows into the Mississippi, Vicksburg is the epitome of Southern heritage and charm. It was incorporated in 1825 and, with its prime locale on the Mississippi, grew into an important port. During the Civil War

Vicksburg, Mississippi

Greenville is Mississippi’s largest river port, set atop the highest point along the Mississippi River between Vicksburg and Memphis. Its rural setting belies a diverse artistic heritage. The Muppets creator Jim Henson was born here, and the city h

Greenville, United States

Teeming with a wide variety of birdlife and a breathtaking array of picturesque landscapes—including deep-green forests, lush wetlands and a patchwork of fertile farmlands—the Lower Mississippi abounds with natural beauty. This portion of America’s great 

Situated on the Chickasaw bluffs overlooking the Mississippi River, Memphis is revered for its blues music and barbecue. Some of the most famed names in blues, including B.B. King, got their start in Memphis, and the city has a well-deserved reputation as

Memphis, Tennessee

The “Queen City of the South” is the birthplace of Memphis blues, popular in vaudeville shows of the early 20th century. With its strong trade in agricultural goods and other natural resources, it grew into one of the South’s largest commercial centers. M

The rich and varied landscape along the Mississippi River is characterized by wide floodplains, rocky outcroppings and sandy beaches nestled between fertile farmland and bustling bankside cities. Indigenous peoples used the river for thousands of years be

Located at the confluence of the Tennessee and Ohio rivers, Paducah is one of Kentucky’s hidden gems. A UNESCO Creative City, Paducah is famed for its preserved 19th-century architecture and historic buildings that line the main street. The city’s Downtow

Paducah, Kentucky

The largest city between St. Louis and Memphis, Cape Girardeau has a long and storied history. It was an important site during the Civil War and once housed a number of forts, including Fort D, which remains a well-preserved historic site to this day. Fon

Cape Girardeau, Missouri

During the 19th century, St. Louis was a gateway into the Louisiana Territory. In 1904, the city gained recognition as host of a world’s fair (officially called the Louisiana Purchase Exposition), whereby some accounts the ice-cream cone was introduced. T

St. Louis, Missouri

St. Louis was once the gateway to the legendary Wild West, known for its gun-wielding cowboys and law-making sheriffs. Today, the city boasts a world-class cultural scene and one of the leading sporting attractions in the US. The St. Louis Cardinals are o

Alton lies along The Meeting of the Great Rivers Scenic Route, where the Mississippi and the Illinois Rivers converge. The road to this historic town is considered one of America’s most picturesque drives, with its limestone river bluffs, flowering trees 

Alton, Illinois

Hannibal is the childhood home of Samuel Langhorne Clemens, or Mark Twain, and the inspiration for his beloved stories of Tom Sawyer and Huckleberry Finn. Prior to the 1803 Louisiana Purchase and arrival of European settlers, a variety of indigenou

Hannibal, Missouri

The US flag was first raised over Iowa in Burlington—in 1805—by Lieutenant Zebulon Pike during his Mississippi explorations. Later, it became an outpost for the American Fur Company, a trading enterprise founded by John Jacob Astor. In 1834, it took its p

Burlington, Canada

Straddling the confluence of the Mississippi and Rock Rivers, the Quad Cities area comprises Davenport and Bettendorf, Iowa, and Rock Island, Moline and East Moline, Illinois. As the only section of the Mississippi that flows from east to west, it is geog

One of Iowa’s few cities laid out among rolling bluffs, Dubuque is called the “Masterpiece on the Mississippi” for its 19th-century ingenuity and modern-day cultural evolution. Timber and boatbuilding were central to the city’s growth, with wood harvested

Dubuque, Iowa

La Crosse has a deep connection to the towering bluffs and rolling farmland of the Norskedalen, or “Norwegian Valley.” Here, a Norwegian immigrant population has created a unique culture over generations. Historic immigrant villages dot the valley still, 

La Crosse, Wisconsin

Red Wing is known for its Red Wing Shoes, which produced footwear for soldiers in both world wars. The city was named after a Sioux chief whose red-dyed swan wing indicated his rank. The first settlers—many from New England—arrived in the mid-1800s. Germa

Red Wing, Minnesota

Bid farewell to your fellow guests and journey home. Or spend more time exploring, perhaps joining one of our extensions.

Saint Paul, United States

Viking Mississippi

Located near the confluence of the Mississippi and Minnesota Rivers, St. Paul welcomed its first settler in 1838. And little more than a decade later, the thriving settlement was named the capital of the Minnesota Territory. By 1858, some 1,000 steamboats

Louisville, Kentucky

Renowned for its southern charm and rich history, Louisville is set along the Ohio River and is the largest city in the state of Kentucky. Perhaps best known as host city for the Kentucky Derby, one of the world’s most prestigious horse races, the city at

Louisville is home to a vibrant culinary scene that rivals its neighbors, celebrating Southern comfort food and contemporary cuisine. The city’s signature dishes include burgoo, a hearty stew with a mix of meats and vegetables, alongside specialty dishes 

Set on the south side of a deep bend in the Ohio River, Owensboro is considered by many to be the cultural and entertainment hub of western Kentucky. Its dedication to music is deeply rooted in its past. Bill Monroe, known as the “Father of Bluegrass,” wa

Owensboro, KY

Nestled on the banks of the Ohio River, the natural landscapes of Henderson have been an inspiration for many of its residents, including the naturalist John James Audubon and blues musician W.C. Handy. Audubon State Park features a museum dedicated to th

Red Wing is known for its Red Wing Shoes, which produced footwear for soldiers in both world wars. The city was named after a Sioux chief whose red-dyed swan wing indicated his rank. The first settlers&mdash;many from New England&mdash;arrived in the mid-

Hannibal is the childhood home of Samuel Langhorne Clemens, or Mark Twain, and the inspiration for his beloved stories of Tom Sawyer and Huckleberry Finn. Prior to the 1803 Louisiana Purchase and arrival of European settlers, a variety of indigen

Nashville, Tennessee

Nestled in the Central Basin of Middle Tennessee, Nashville is beloved as one of the South’s most influential country music cities. With its location on the Cumberland River, it experienced a rapid rise after its founding in 1779. In the 19th century, the

Clarksville is a city steeped in history and rich in culture. Nestled along the shores where the meandering Cumberland River meets the Red River, it was established in 1785 and named after General George Rogers Clark, a Revolutionary War soldier and front

Clarksville, Tennessee

America’s iconic Mississippi River offers a deep dive into the heart and soul of the U.S. From vibrant New Orleans to the bustling cities of St. Louis and Minneapolis, a cruise on the Mississippi presents a rich tapestry of American culture, history, and landscapes. It’s perfect for those looking to experience classic Americana, including the origins of blues and jazz music, on one of the world’s most famous rivers.

Cruisebound

Book Your Dream River Cruise

Why book with Cruisebound?

Competitive pricing

Flexible payments

No hidden fees

Hold for free

Top-rated Mississippi cruises

21 Night Mississippi River Odyssey

7 Night Heartland Of America

14 Night America's Great River

7 Night Mississippi & Ohio River Explorer

14 Night Bayous,Blues & Bluegrass

14 Night The Big Easy To The Gateway City

7 Night Heartland Of America

7 Night Mississippi & Ohio River Explorer

7 Night Nashville,Memphis & The Cumberland

7 Night Mississippi Delta Explorer

Why travel down the Mississippi?

Book with top river cruise lines

Why travel on a scenic river cruise?

Why book with Cruisebound?

Competitive pricing

Flexible payments

No hidden fees

Hold for free

Top-rated Mississippi cruises

21 Night Mississippi River Odyssey

7 Night Heartland Of America

14 Night America's Great River

7 Night Mississippi & Ohio River Explorer

14 Night Bayous,Blues & Bluegrass

14 Night The Big Easy To The Gateway City

7 Night Heartland Of America

7 Night Mississippi & Ohio River Explorer

7 Night Nashville,Memphis & The Cumberland

7 Night Mississippi Delta Explorer

Why travel down the Mississippi?

Book with top river cruise lines

Why travel on a scenic river cruise?

Access to Major and Historic Cities

Intimate, Personalized Experience

Immersive Cultural Encounters

Leisurely Pace, Scenic Views

Convenience and Comfort