Find and compare cruises to South America in 2025 with Princess. Get cruise deals, including last-minute deals.

Book cruises to South America in 2025 with Princess Online and Save

Cruisebound

57 Night World Cruise aboard the Crown Princess departing from Dover (London), England, on 2025-07-30, cruises to Bergen, Norway, Skjolden, Norway, Honningsvag (North Cape), Norway, Reykjavik, Iceland, Isafjord, Iceland, Nanortalik, Greenland, Qaqortoq, Greenland, Halifax, Nova Scotia, New York, New York, New York, New York, Miami, Florida, Cartagena, Colombia, Panama Canal Full Transit New Locks, Callao (Lima), Peru, Callao (Lima), Peru, Pisco (Puerto San Martin), Peru, Easter Island, Chile, Adamstown, Pitcairn Island, Papeete, Tahiti, French Polynesia, Papeete, Tahiti, French Polynesia, Moorea, French Polynesia, X Intl Date Line, Auckland, New Zealand and Sydney, Australia, starting at 7898.0 per person.

57 Night World Cruise

53 Night South America Cruise aboard the Sapphire Princess departing from Los Angeles, California, on 2025-11-16, cruises to Manzanillo, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama, Manta (Quito), Ecuador, Callao (Lima), Peru, Callao (Lima), Peru, Pisco (Puerto San Martin), Peru, Coquimbo (La Serena), Chile, San Antonio, Chile, Puerto Montt, Chile, Chacabuco, Chile, Amalia (Skua) Glacier, Chile, Punta Arenas, Chile, Ushuaia, Argentina, Cape Horn (scenic Cruising), Stanley, Falkland Islands, Puerto Madryn, Argentina, Montevideo, Uruguay, Buenos Aires, Argentina, Buenos Aires, Argentina, Buenos Aires, Argentina, Punta Arenas, Chile, Ushuaia, Argentina, Antarctic Peninsula, Antarctica, Antarctic Peninsula, Antarctica, Antarctic Peninsula, Antarctica, Antarctic Peninsula, Antarctica, Stanley, Falkland Islands, Montevideo, Uruguay and Buenos Aires, Argentina, starting at 6498.0 per person.

53 Night South America Cruise

36 Night World Cruise aboard the Crown Princess departing from New York, New York, on 2025-08-20, cruises to Miami, Florida, Cartagena, Colombia, Panama Canal Full Transit New Locks, Callao (Lima), Peru, Callao (Lima), Peru, Pisco (Puerto San Martin), Peru, Easter Island, Chile, Adamstown, Pitcairn Island, Papeete, Tahiti, French Polynesia, Moorea, French Polynesia, Papeete, Tahiti, French Polynesia, X Intl Date Line, Auckland, New Zealand and Sydney, Australia, starting at 4398.0 per person.

36 Night World Cruise

36 Night South America Cruise aboard the Sapphire Princess departing from Los Angeles, California, on 2025-11-16, cruises to Manzanillo, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama, Manta (Quito), Ecuador, Callao (Lima), Peru, Callao (Lima), Peru, Pisco (Puerto San Martin), Peru, Coquimbo (La Serena), Chile, San Antonio, Chile, Puerto Montt, Chile, Chacabuco, Chile, Amalia (Skua) Glacier, Chile, Punta Arenas, Chile, Ushuaia, Argentina, Cape Horn (scenic Cruising), Stanley, Falkland Islands, Puerto Madryn, Argentina, Montevideo, Uruguay, Buenos Aires, Argentina and Buenos Aires, Argentina, starting at 3248.0 per person.

36 Night South America Cruise

17 Night South America Cruise aboard the Sapphire Princess departing from Buenos Aires, Argentina, on 2025-12-22, cruises to Punta Arenas, Chile, Ushuaia, Argentina, Antarctic Peninsula, Antarctica, Antarctic Peninsula, Antarctica, Antarctic Peninsula, Antarctica, Antarctic Peninsula, Antarctica, Stanley, Falkland Islands and Montevideo, Uruguay, starting at 3148.0 per person.

17 Night South America Cruise

16 Night South America Cruise aboard the Sapphire Princess departing from San Antonio, Santiago, Chile, on 2025-12-06, cruises to Puerto Montt, Chile, Chacabuco, Chile, Amalia (Skua) Glacier, Chile, Punta Arenas, Chile, Ushuaia, Argentina, Cape Horn (scenic Cruising), Stanley, Falkland Islands, Puerto Madryn, Argentina, Montevideo, Uruguay, Buenos Aires, Argentina and Buenos Aires, Argentina, starting at 1634.0 per person.

16 Night South America Cruise

20 Night South America Cruise aboard the Sapphire Princess departing from Los Angeles, California, on 2025-11-16, cruises to Manzanillo, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama, Manta (Quito), Ecuador, Callao (Lima), Peru, Callao (Lima), Peru, Pisco (Puerto San Martin), Peru and Coquimbo (La Serena), Chile, starting at 1548.0 per person.

20 Night South America Cruise

14 Night Caribbean - Southern Cruise aboard the Coral Princess departing from Fort Lauderdale (Port Everglades), Florida, on 2025-11-24, cruises to St. Maarten, Netherlands Antilles, Port of Basseterre, St. Kitts, St. Kitts and Nevis, Dominica, Caribbean, Fort-de-France, Martinique, St. Georges, Grenada, West Indies, Trinidad, Trinidad and Tobago, Port of Oranjestad, Aruba, Caribbean and Curacao, Caribbean, starting at 948.0 per person.

14 Night Caribbean - Southern Cruise

12 Night Transcanal Cruise aboard the Caribbean Princess departing from Fort Lauderdale (Port Everglades), Florida, on 2025-11-17, cruises to Port of Oranjestad, Aruba, Caribbean, Curacao, Caribbean, Cartagena, Colombia, Panama Canal,partial Transit, Colon, Panama, Puerto Limon, Costa Rica and Ocho Rios, Jamaica, starting at 668.0 per person.

12 Night Transcanal Cruise

16 Night Transcanal Cruise aboard the Island Princess departing from San Francisco, California, on 2025-12-07, cruises to Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama, Panama Canal Full Transit Historic Locks, Cartagena, Colombia and Fort Lauderdale (Port Everglades), Florida, starting at 628.0 per person.

16 Night Transcanal Cruise

Popular Sailings

 Fort Lauderdale (Port Everglades)

Dover (London), England

Los Angeles

Sydney, Australia

Buenos Aires

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Crown Princess

Sapphire Princess

Island Princess

Coral Princess

Caribbean Princess

Browse Cruise Ships

Bergen, Norway

Skjolden, Norway

Honningsvag (North Cape), Norway

Reykjavik, Iceland

Isafjord, Iceland

Nanortalik, Greenland

Qaqortoq, Greenland

Halifax, Nova Scotia

New York, New York

Miami, Florida

Cartagena, Colombia

Panama Canal Full Transit New Locks

Callao (Lima), Peru

Pisco (Puerto San Martin), Peru

Easter Island, Chile

Adamstown, Pitcairn Island

Papeete, Tahiti, French Polynesia

Moorea, French Polynesia

X Intl Date Line

Auckland, New Zealand

Princess Cruises

Los Angeles, California

Manzanillo, Mexico

Puntarenas, Costa Rica

Fuerte Amador, Panama

Manta (Quito), Ecuador

Coquimbo (La Serena), Chile

San Antonio, Chile

Puerto Montt, Chile

Chacabuco, Chile

Amalia (Skua) Glacier, Chile

Punta Arenas, Chile

Ushuaia, Argentina

Cape Horn (scenic Cruising)

Stanley, Falkland Islands

Puerto Madryn, Argentina

Montevideo, Uruguay

Buenos Aires, Argentina

Antarctic Peninsula, Antarctica

San Antonio, Santiago, Chile

Fort Lauderdale (Port Everglades), Florida

St. Maarten, Netherlands Antilles

Port of Basseterre, St. Kitts, St. Kitts and Nevis

Dominica, Caribbean

Fort-de-France, Martinique

St. Georges, Grenada, West Indies

Trinidad, Trinidad and Tobago

Port of Oranjestad, Aruba, Caribbean

Curacao, Caribbean

Panama Canal,partial Transit

Colon, Panama

Puerto Limon, Costa Rica

Ocho Rios, Jamaica

San Francisco, California

Puerto Vallarta, Mexico

Puerto Quetzal, Guatemala

Panama Canal Full Transit Historic Locks

South America