Find and compare cruises to South America in 2025 with Costa. Get cruise deals, including last-minute deals.

Book cruises to South America in 2025 with Costa Online and Save

Cruisebound

17 Night Transatlantic Cruise aboard the Costa Favolosa departing from Marseille, France, on 2025-11-03, cruises to Barcelona, Spain, Cadiz (Seville), Spain, Lisbon, Portugal, Funchal, Madeira, Portugal, Santa Cruz de Tenerife, Canary Islands, Praia, Cape Verde, Recife, Brazil, Maceio, Brazil and Bahia de Salvador, Brazil, starting at 1723.0 per person.

17 Night Transatlantic Cruise

7 Night South America Cruise aboard the Costa Diadema departing from Santos (Sao Paulo), Brazil, on 2025-12-21, cruises to Buenos Aires, Argentina, Montevideo, Uruguay and Itajai, Brazil, starting at 1334.0 per person.

7 Night South America Cruise

16 Night Transatlantic Cruise aboard the Costa Favolosa departing from Genoa, Italy, on 2025-11-02, cruises to Marseille, France, Barcelona, Spain, Cadiz (Seville), Spain, Lisbon, Portugal, Funchal, Madeira, Portugal, Santa Cruz de Tenerife, Canary Islands, Praia, Cape Verde and Recife, Brazil, starting at 1611.0 per person.

16 Night Transatlantic Cruise

7 Night Caribbean Cruise aboard the Costa Fascinosa departing from Santo Domingo, Dominican Republic, on 2025-12-08, cruises to Catalina Island, Dominican Republic, Fort-de-France, Martinique, Guadeloupe, Caribbean, Port of Basseterre, St. Kitts, St. Kitts and Nevis and Tortola, B.V.I., starting at 895.0 per person.

7 Night Caribbean Cruise

14 Night Caribbean Cruise aboard the Costa Pacifica departing from La Romana, Dominican Republic, on 2025-12-28, cruises to Catalina Island, Dominican Republic, Samana, Dominican Republic, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Cabo Rojo, St. Lucia, Caribbean, Bridgetown, Barbados, Guadeloupe, Caribbean, Port of Basseterre, St. Kitts, St. Kitts and Nevis and Tortola, B.V.I., starting at 1495.0 per person.

14 Night Caribbean Cruise

19 Night Transatlantic Cruise aboard the Costa Diadema departing from Maceio, Brazil, on 2025-04-24, cruises to Praia, Cape Verde, Santa Cruz de Tenerife, Canary Islands, Funchal, Madeira, Portugal, Cadiz (Seville), Spain, Lisbon, Portugal, Lisbon, Portugal, Vigo, Spain, Le Havre (Paris), France, Southampton, England and Rotterdam, The Netherlands, starting at 1452.28 per person.

19 Night Transatlantic Cruise

14 Night Transatlantic Cruise aboard the Costa Favolosa departing from Barcelona, Spain, on 2025-11-04, cruises to Cadiz (Seville), Spain, Lisbon, Portugal, Funchal, Madeira, Portugal, Santa Cruz de Tenerife, Canary Islands, Praia, Cape Verde and Recife, Brazil, starting at 1446.0 per person.

14 Night Transatlantic Cruise

7 Night South America Cruise aboard the Costa Diadema departing from Itajai, Brazil, on 2025-12-20, cruises to Santos (Sao Paulo), Brazil, Buenos Aires, Argentina and Montevideo, Uruguay, starting at 1275.0 per person.

8 Night Caribbean Cruise aboard the Costa Fascinosa departing from Fort-de-France, Martinique, on 2025-12-31, cruises to St. John's, Antigua, Guadeloupe, Caribbean, Port of Basseterre, St. Kitts, St. Kitts and Nevis, Tortola, B.V.I., Santo Domingo, Dominican Republic and Catalina Island, Dominican Republic, starting at 1254.0 per person.

8 Night Caribbean Cruise

7 Night Caribbean Cruise aboard the Costa Fascinosa departing from Santo Domingo, Dominican Republic, on 2025-12-15, cruises to Catalina Island, Dominican Republic, Fort-de-France, Martinique, Guadeloupe, Caribbean, St. Maarten, Netherlands Antilles and Port of Basseterre, St. Kitts, St. Kitts and Nevis, starting at 880.0 per person.

Popular Sailings

Sao Paulo

Marseille

Barcelona

Itajai

Buenos Aires

Explore Departure Ports

Costa Diadema

Costa Favolosa

Costa Fascinosa

Costa Pacifica

Costa Deliziosa

Browse Cruise Ships

Marseille, France

Barcelona, Spain

Cadiz (Seville), Spain

Lisbon, Portugal

Funchal, Madeira, Portugal

Santa Cruz de Tenerife, Canary Islands

Praia, Cape Verde

Recife, Brazil

Maceio, Brazil

Bahia de Salvador, Brazil

Costa Cruise Lines

Santos (Sao Paulo), Brazil

Buenos Aires, Argentina

Montevideo, Uruguay

Itajai, Brazil

Genoa, Italy

Santo Domingo, Dominican Republic

Catalina Island, Dominican Republic

Fort-de-France, Martinique

Guadeloupe, Caribbean

Port of Basseterre, St. Kitts, St. Kitts and Nevis

Tortola, B.V.I.

La Romana, Dominican Republic

Samana, Dominican Republic

Grand Turk, Turks and Caicos

Amber Cove, Dominican Republic

Cabo Rojo

St. Lucia, Caribbean

Bridgetown, Barbados

Vigo, Spain

Le Havre (Paris), France

Southampton, England

Rotterdam, The Netherlands

St. John's, Antigua

St. Maarten, Netherlands Antilles

South America