Find and compare cruises to the Mediterranean in 2026 with MSC Cruises. Get cruise deals, including last-minute deals.

Book cruises to the Mediterranean in 2026 with MSC Cruises Online and Save

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7 Night Mediterranean - Western Cruise aboard the MSC Splendida departing from Civitavecchia (Rome), Italy, on 2025-05-13, cruises to Genoa, Italy, Marseille, France, Tarragona, Spain, Valencia, Spain and Livorno (Florence/Pisa), Italy, starting at 423.0 per person.

7 Night Mediterranean - Western Cruise

7 Night Mediterranean Cruise aboard the MSC Seaview departing from Marseille, France, on 2026-05-01, cruises to Genoa, Italy, Civitavecchia (Rome), Italy, Palermo, Sicily, Italy, Ibiza, Spain and Barcelona, Spain, starting at 919.0 per person.

7 Night Mediterranean Cruise

5 Night Mediterranean - Eastern Cruise aboard the MSC Fantasia departing from Naples, Italy, on 2025-04-26, cruises to Heraklion, Crete, Greece, Santorini (Thira), Greece and Istanbul, Turkey, starting at 509.0 per person.

5 Night Mediterranean - Eastern Cruise

10 Night Grand Voyage Cruise aboard the MSC Preziosa departing from Vigo, Spain, on 2026-04-16, cruises to Gijon, Spain, Southampton, England, Le Havre (Paris), France, Zeebrugge (Bruges), Belgium, Copenhagen, Denmark, Oslo, Norway and Hamburg, Germany, starting at 2877.0 per person.

10 Night Grand Voyage Cruise

5 Night Mediterranean Cruise aboard the MSC Magnifica departing from Marseille, France, on 2025-12-16, cruises to Barcelona, Spain, Civitavecchia (Rome), Italy and Genoa, Italy, starting at 359.0 per person.

5 Night Mediterranean Cruise

5 Night Mediterranean Cruise aboard the MSC Magnifica departing from Genoa, Italy, on 2025-12-15, cruises to Marseille, France, Barcelona, Spain and Civitavecchia (Rome), Italy, starting at 359.0 per person.

7 Night Europe - Northern Cruise aboard the MSC Virtuosa departing from Southampton, England, on 2025-05-31, cruises to La Rochelle, France, Bilbao, Spain, La Coruna, Spain and Cherbourg, France, starting at 591.0 per person.

7 Night Europe - Northern Cruise

10 Night Mediterranean Cruise aboard the MSC Fantasia departing from Trieste, Italy, on 2025-10-29, cruises to Zadar, Croatia, Dubrovnik, Croatia, Bari, Italy, Corfu, Greece, Valletta, Malta, Messina, Sicily, Italy, Civitavecchia (Rome), Italy and Barcelona, Spain, starting at 1033.0 per person.

10 Night Mediterranean Cruise

6 Night Grand Voyage Cruise aboard the MSC Armonia departing from Venice, Italy, on 2025-11-24, cruises to Zadar, Croatia, Dubrovnik, Croatia, Civitavecchia (Rome), Italy and Barcelona, Spain, starting at 339.0 per person.

6 Night Grand Voyage Cruise

5 Night Mediterranean - Western Cruise aboard the MSC Magnifica departing from Genoa, Italy, on 2025-05-05, cruises to Marseille, France, Barcelona, Spain and Barcelona, Spain, starting at 319.0 per person.

5 Night Mediterranean - Western Cruise

Popular Sailings

Marseille

Genoa, Italy

Barcelona

Rome (Civitavecchia)

Naples

Explore Departure Ports

MSC Orchestra

MSC World Europa

MSC Splendida

MSC Seaview

MSC Musica

Browse Cruise Ships

Civitavecchia (Rome), Italy

Marseille, France

Tarragona, Spain

Valencia, Spain

Livorno (Florence/Pisa), Italy

MSC Cruises

Palermo, Sicily, Italy

Ibiza, Spain

Barcelona, Spain

Naples, Italy

Heraklion, Crete, Greece

Santorini (Thira), Greece

Istanbul, Turkey

MSC Fantasia

Vigo, Spain

Gijon, Spain

Southampton, England

Le Havre (Paris), France

Zeebrugge (Bruges), Belgium

Copenhagen, Denmark

Oslo, Norway

Hamburg, Germany

MSC Preziosa

MSC Magnifica

La Rochelle, France

Bilbao, Spain

La Coruna, Spain

Cherbourg, France

MSC Virtuosa

Trieste, Italy

Zadar, Croatia

Dubrovnik, Croatia

Bari, Italy

Corfu, Greece

Valletta, Malta

Messina, Sicily, Italy

Venice, Italy

MSC Armonia

Mediterranean